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yregtoday at 6:22 AM9 repliesview on HN

The researchers seem pretty convinced that this mushroom causes the hallucinations yet they do not describe trying it out in an experiment.

Surely the most straightforward way is to undercook the mushrooms and run a blind controlled experiment where participants eat the shrooms and report on hallucinations.

What stopped them?


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noviatoday at 7:13 AM

> the trips it produces are unusually long, commonly lasting one to three days after an onset of 12 to 24 hours, and in some cases even causing hospital stays of up to a week. Because of the extraordinarily long duration of these trips and the chance for prolonged side effects such as delirium and dizziness, Domnauer has yet to try the raw mushrooms himself.

> These mega-trips might help to explain why people in China, the Philippines and Papua New Guinea do not seem to have a tradition of purposefully seeking out L. asiatica for its psychoactive effects, according to Domnauer's findings. "It was always just eaten for food," Domnauer says, with hallucinations being an unexpected side-effect.

From when this same story was covered in January

https://www.bbc.com/future/article/20260121-the-mysterious-m...

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lukantoday at 7:57 AM

Do you volunteer?

3 day non stop trip sounds .. not great, if it ain't great.

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pikertoday at 6:53 AM

Maybe the prospect of seeing tiny people? Stops me!

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comboytoday at 9:05 AM

> What stopped them?

https://en.wikipedia.org/wiki/Ethics_committee

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colordropstoday at 7:30 AM

They might be neurotoxic.

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wellthisisgreattoday at 6:55 AM

Tiny people

theelous3today at 10:27 AM

> Domnauer has yet to try the raw mushrooms himself

Coward, basically. I have no idea why on earth you'd travel the world looking for a specific hallucinogen and then just try to sequence it and toss it, and then waste everyone's time writing papers saying you essentially have a hunch about the mushroom's effects.

Beyond terrible science.

s1artibartfasttoday at 6:38 AM

I assume knowlege of the experiment could influence the outcome.

I think you would have to dose people without knowledge of that phenomenon

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forestrywattoday at 6:26 AM

Presumably the fact that experimenting on oneself is not considered particularly ethical or repeatable for science?

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