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derektanktoday at 6:39 AM3 repliesview on HN

There’s nothing unethical about self experimentation. There are many notable examples of it in the history of science. Most notable is probably Barry Marshall’s decision to self-dose with helicobacter pylori, in an effort to prove that the bacteria caused ulcers. They did, he treated himself with antibiotics, and he was later awarded a Nobel for the research. Werner Forssman also won a Nobel for work partially derived from self-applying a cardiac catheter.


Replies

wraptiletoday at 7:05 AM

Barry Marshall's story is so iconic that I read it every time despite knowing it very well.

That being said one claim here would be that allowing self-experimentation would pressure people into self experimenting due to how our academia and labs are structured these days i.e. a junior scientists could be pressured into self experimentation by their superiors. So this is definitely not as clear-cut as one might think.

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jpfromlondontoday at 1:10 PM

evidently you are unfamiliar with experimental science or clinical trials, like it or not self experimentation and the consumption/administration of psychoactive substances is considered unethical, rightly or wrongly.

In the case of self-testing it raises concerns of objectivity, not just in terms of perception and observation but with regards to bias and intent, throwing into question the results and reasons for the study.

kapeptoday at 8:43 AM

> There’s nothing unethical about self experimentation.

If people get rewarded for self experimentation, either directly with prices or indirectly with fame and success, more people will try do it. That certainly does raise ethical concerns. It worked out for people you mentioned but there will be many others who might harm themselves doing it.