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hattmallyesterday at 5:51 PM1 replyview on HN

Are you implying the medicine did it or does the medicine just make you eat less which cleared it? Like is there an MOA of the drug itself?


Replies

declan_robertsyesterday at 6:18 PM

Yes the medicine does it. It's attacking T2D via several pathways, but in the case of Reta the glucagon is doing the heavy lifting of clearing liver fat.

This extra receptor is why Reta is a triple agonist unlike semaglutide (single glp1) or tirzepatide (glp1+gip double agonist).