OTS and long-covid are remarkably similar
once the body/brain/CNS starts treating cytokines produced by exercise (and illness) as a pathogen instead of doing stress adaptations, you will become perpetually ill and unable to exceed aerobic threshold (or lactate threshold) without PEM
and there's no escape, no amount of rest will cure it, there's no supplement or drug that will reprogram your mitochondria at that point
and right now all research is effectively dead for long-covid, forget OTS which will never happen