There are a lot of cases where I go direct-to-vendor. Particularly for niche products such as supplements and men's cosmetics, it is easier to find one or two trustworthy distributors or manufacturers who have most of what I want.
There has been a lot of consolidation in this space. Part of that means that independent webstores closed up and moved exclusively to Amazon. If they did not close up shop, they now use Shop/Shopify or a similar SaaS, which streamlines sign-ups, sign-ins, and checkouts, for better or worse. All the better if you've got PayPal or Apple/Google Pay.
I've noticed that a lot of "click and mortar" stores have really abysmal product on their physical shelves. Like, it's discontinued, or all the wrong sizes, subtly defective, or just undesirable. It's like their stores are kind of dumping grounds, and it makes sense, because the sort of person in 2026 who gets in a car, and shops in a store, and grabs stuff uncritically off the shelf is not your most discerning or astute shopper.
Target's shopping experience remains better than most. Their stores include everyday needs like groceries and medicine, so I can meet a lot of my needs by dropping in. Furthermore, their app-based shopping (marketplace) is pretty good too, so if I need housewares delivered or something, or I need to look up something and find it right now, in-store, their app is right there. And their shopping carts now have little dedicated slots to drop in your smartphone next to the cupholders.
The best online shopping is Office Depot/OfficeMAX. They've shrunk their retail footprint, but their online store is still a non-marketplace, and really good for buying the kinds of things they sell. That includes some non-intuitive buys, like you can find kitchen supplies, because they stock many breakrooms for small/medium businesses. Good place for electronics and accessories and art supplies, even if you are just comparison-shopping. Their delivery is rapid and often just comes from the nearest store!