logoalt Hacker News

anonymarstoday at 3:53 PM1 replyview on HN

Your reading comprehension is way off. The article says "Each year in Australia, up to 420 people are diagnosed with acral or mucosal melanomas. They affect people of all ethnic backgrounds, and are the most common forms of melanoma in people with very dark skin."

That is a discussion of specific subtypes of melanoma. You've turned that into a general statement about melanoma:

> not all skin cancers are caused by sun exposure, and this is more true for Melenoma which occur both more frequently in darker skinned people and in place where there is little sun exposure.

These are "Two rare ... forms of melanoma" not "melanoma as a whole." The article does not say melanoma as a whole is more frequent in darker-skinned people and in places with little sun exposure. Those two subtypes are.

Let's also quote from https://wasatchdermatology.com/blogs/basal-cell-vs-squamous-...

> BCC ... can cause significant local tissue damage if left untreated. Most cases are linked to chronic sun exposure, especially in fair-skinned individuals.

> While it often remains localized at first, SCC can invade deeper tissues and, in some cases, metastasize to lymph nodes or other organs. Risk factors include cumulative sun exposure, a history of sunburns, and immunosuppression.

> While not all skin cancers can be prevented, effective sun protection and healthy habits can greatly reduce your risk for basal cell carcinoma, squamous cell carcinoma, and melanoma.

That does not support "most skin cancers are not a big deal"

> Melanomas can vanish on their own

Your link does not support that statement https://www.nature.com/articles/s41379-021-00870-2

"Whilst some studies reported an association with improved survival ... others did not find any significant association, and some even reported worse outcomes in patients whose tumors showed regression"

You seem to have read this as "melanoma just goes away and the problem is gone" rather than "the primary tumor can recede, and in that case survival odds are somewhat better by a few percentage points (but actually worse for Stage III patients!)"


Replies

Noaiditoday at 7:57 PM

5-year relative survival rates for melanoma skin cancer is 95%. That is all that matters.

https://www.cancer.org/cancer/types/melanoma-skin-cancer/det...

The study data is not out yet, I thought it was, so I will wait untiul it is to comment further.

But saying in the press that:

https://www.abc.net.au/news/2026-08-20/melanoma-drug-cancer-...

"Melanoma is one of the deadliest forms of skin cancer, with more than 330,000 new cases diagnosed worldwide in 2022."

Saying melanoma is the deadliest forms of skin cancer is not revealing anything and is a scare tactic. In 2022, there were approximately 60,000 deaths worldwide due to melanoma. A rare cancer with 18% death rate is not high compared to the others. The deadliest cancers include lung cancer, pancreatic cancer, liver cancer, colorectal cancer, and breast cancer. These cancers have the lowest survival rates and account for a significant number of cancer-related deaths.

But I will wait for the upcoming complications and the worse 5 year all cause mortality rate in these patients.

show 1 reply