For most, if not all users, the crease is not something one notices during regular use. You just forget it's there when you look at content.
That said, with the Pixel's enormous crease you feel it if you touch the middle of the screen.
Depends on your use. If you draw or want high quality display with no weird reflections from your tablet then it's a non starter.
Depends on your use. If you draw or want high quality display with no weird reflections from your tablet then it's a non starter.