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A_D_E_P_Ttoday at 9:35 AM0 repliesview on HN

The most famous drug is donepezil (Aricept). This is very weakly effective on the whole. In most Alzheimer's sufferers, there is no effect. But some people respond well to it: https://pmc.ncbi.nlm.nih.gov/articles/PMC2328349

Galantamine, which is mechanistically similar, is another option. Interestingly, it's a natural product, which you can extract from the common snowdrop flower, galanthus nivalis, and many other plants.

Benzgalantamine, a galantamine prodrug, was approved in 2024. This has been, like many recent FDA approvals, somewhat controversial: https://ebm.bmj.com/content/early/2026/02/26/bmjebm-2025-114...

These drugs are, at best, stopgaps. There are no real mitigation regimes.