For work-from-home, I can't emphasize enough how much of a game changer it is to have a physically separate building for your work, especially if you have a family with kids and noise and pets and things. Working from a spare bedroom, even one without a bed / outfitted as an office, is just not my thing. Even if your family "knows the rules" and let you work in peace. It subjectively still "feels like you're home". With a separate building, I can do a short walking commute and take those 10 seconds to "get into work mindset." And, once I'm out there, it can be a hermetically sealed, zero-distraction zone.

If you are lucky and fortunate enough to live in an actual house with land, and work (or are thinking about working) remotely, seriously consider investing in an actual separate building for your office.