alt Hacker NewsSo I can somewhat speak to this, as I actually did this for a while c. 2021 and 2022.
The issue (apart from my Mac mini still having the old, bigger form factor back then) is that this requires a full shutdown (obviously), and that is more friction than opening a closed laptop lid. It just takes a moment for every app and background service etc. to settle back in after, and depending on how your brain works, you might not like that a whole lot.
It absolutely is a cool feeling to carry a pretty mighty desktop in the backpack, though.
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I did this for a few years, going further back in time.
The shutdown thing didn't bother me, and in fact the Mini was lighter than a Macbook Air at the time. So all in all it was pretty convenient.
What if you have some battery system working? Then technically, you could travel with it
I think it's actually good to have a forced reboot from time to time, but then I'm not very disciplined in closing stuff I'm no-longer using! Especially like docker containers I was using months ago, that I forgot to shutdown.