logoalt Hacker News

malfistyesterday at 9:17 PM4 repliesview on HN

This has been tested actually. A clinical trial looking at tight blood sugar regulation was aborted after it resulted in multiple cardiac events.


Replies

RHSeegeryesterday at 10:20 PM

That's not a fair representation of what happened. That study was going for _aggressive_ control - beyond what any normal person would do. They were combining multiple drugs to force blood sugar down rapidly, including right after meals (when it _should_ be going up).

Paying more attention to your blood sugar and acting reasonably to keep it in check isn't giving anyone heart attacks.

From the AI

> The concern was not that lower glucose is inherently bad. Rather, pushing blood sugar down rapidly and very tightly—especially with insulin and multiple glucose-lowering drugs—caused more episodes of hypoglycemia, weight gain, and treatment complexity. Severe low blood sugar can trigger abnormal heart rhythms and other cardiovascular stress. The intensive-treatment arm was stopped early after about 3.5 years because it had a higher death rate, although the exact mechanism was not definitively established.

adinisomyesterday at 10:23 PM

Interesting! Found this overview: https://emcrit.org/pulmcrit/tight-glycemic-control/

andy_ppptoday at 12:35 AM

Nonsense, you can fast or live in ketosis for years without any adverse consequences.