I know of at least 5 different UI frameworks in different languages which are partially accessible or completely inaccessible. Some include Dlangui, Tkinter (although this is getting better), DearImGui... Really any UI that decides to draw it's widgets by frame. QT also has some accessibility problems. In apps made with any of these, they are either impossible to use with assistive technology (and therefore the keyboard) or they are very difficult to use.