Depends what you think the purpose of MFA is.
By and large, I see it as protection for the service provider, not for the me - they prevent the service provider from having to deal with people using weak passwords or re-using passwords that get leaked.
By-and-large, given the option, I wouldn't enable MFA - I appropriately store my strong, unique passwords, and am satisfied with that level of security.
Having MFA forced on my is purely a convenience downgrade without any real security upgrade, and having my password manager automatically fill MFA tokens minimizes that convenience downgrade.