If you think about it a little harder, the pattern isn't just gender but "thing you are standing out for".

In the Holmes case, she was visibly celebrated for being a young female (as a positive) so it's not shocking that it flipped to a negative on people's mind when she was proven to be a fraud.

In the case of SBF, he wasn't celebrated for being male. But he was notable for his association with "effective altruism". Has the reputation of the EA community been adversely affected by his downfall? Absolutely. So that's the more part analogy here.