The psychopathic tell is dismissing political activism as "trying to derive meaning." It's right up there with the idea that moral or ethical claims are "performative".
These kinds of claims generally come from people who don't feel any moral or ethical impulses. These people are most commonly malignant narcissists and psychopaths. A great example is Elon Musk who described empathy as a "bug".
Morality is a fundamental feature for most humans. The people who make the kinds of claims above constitute a small, single digit percentage of the population. They tend to have an outsize influence though, because they exploit the trust of others to rise to positions of power, where their lack of compunction can be an advantage.
People like Trump, Musk, and Thiel are canonical examples of this. Eventually, when their actions make things bad enough for everyone else, people tend to take action. We may be approaching a time like that. You acknowledged this yourself in earlier comments.
Most of what people call morality is just their own feelings or interest or some attempt to protect their ego, it's basically just an expression of narcissism.
The cultivation of a sense of actual morality requires a lot of study and humility and quieting your own feelings and ego. This is very difficult and most people can't do it, ideally in a healthy society the elites you have are people who can and do do this.
Ironically Thiel in particular is precisely one of these people. He's very thoughtful and well read and displays a lot of humility in his speech and conduct.
There are many things I consider to be deeply immoral that I nevertheless cannot change. My political activism is merely performative.
Power and wealth are already so entrenched I think we have little chance of effecting any lasting change without violence. So either I become a literal terrorist, or I enable Daniel Plainview mode. It seems to me like the rational move is to try to get rich by any means necessary so I can fuck off to somewhere isolated and never have to deal with the rotten society I hate ever again.