If you have their IP addresses in your dashboard, go to Google Ads > Admin > Account Settings > IP Exclusions. Then, add the entire network/data center range there (i.e. 123.4.5.*). In 99% of cases, these bot networks are not run from residential providers. You can confirm IPs at https://ipgeolocation.io/

After running Google Ads for a couple of years, our current exclusion list has over 4000 networks just in the US.