I'm confused by this. I remember genetically modifying E. coli to glow in the dark in high school. You can apparently buy a kit to do it online for $39.99 USD.
I'm not suggesting that making bacteria glow in the dark is the same as making arbitrary changes to a virus. At the same time, do you really need $100M of automated freezers and cell culture rooms? Do you need to synthesise a whole virus? Presumably you could just find a building in the desert, shoot anyone who goes near it, feed the past decade of gain-of-function research into Qwen, splice stuff into viruses based on the most promising leads Qwen gave your biologists, then infect some immunosuppressed political prisoners and see who dies fastest.
I would have thought the main thing stopping people is that this is a clearly stupid thing to do and offers little strategic advantage. But at some point it'll be cheap enough for you or I to do it with a little AI assistance, right? Or at least within the capabilities of an Aum Shinrikyo style doomsday cult.
Is it, err, possible to then transplant the e coli strain to one's gut biome?
> I remember genetically modifying E. coli to glow in the dark in high school.
That was a fun class! I haven't encountered anyone else outside a students who went to my one HS in Seattle during the late 90s / early 2000s who also remember doing that, interesting to hear other schools had a similar class.