I've had to explain to people that lifting something as simple as a case of bottled water can be genuinely difficult after eight-ish years of feminizing HRT.

It's gradual, it's not all at once and I am still slightly taller and heavier-set than the average American woman, so I do have an advantage through having more mass, but anyone that's larger than the average American woman will also have that so it's not really an advantage, just a fact of having a larger body.