It's cooled down a lot in the last few years, since peak woke passed. But I think that a few years ago, there would have been serious danger of being fired at many companies in the US if you refused to use a trans person's chosen pronouns. Now, one might say, this is just a matter of basic politeness... why wouldn't you use them? However, consider the situation if a white coworker started insisting that people refer to him as black, and you could get fired for not referring to him as black. For the sake of a better comparison, let's say that the white coworker was doing medical treatments to increase skin melanin, hair curliness, and so on.
As for trans genocide, I mean sure, you can make an argument that there is a trans genocide by really really stretching the meaning of the word "genocide" or by using certain parts of highly technical definitions of "genocide". But when trans activists speak of "trans genocide", they are trying to appeal to the emotional resonance of more popularly central examples of genocides, ones with mass killings. If we use the common meaning of the word "genocide", the one that is intended the vast majority of the time the word is used, there is no trans genocide.
As for washrooms, note that I never said that I'm against trans people using their chosen genders' washrooms. What I said is that many trans activists pushed to do this long before the American public had become ready for something of that nature, which contributed to a backlash against the trans movement in general.