If we are talking about pure/theoretical mathematics, then the vast majority of the problems people pose and solve have at best tangential relationship with applications, and a big part even is only related to other math problems. Of course quite a bit of mathematics historically emerged as this kind of intellectual endeavour to find applications later, but there is neither a way to predict which ones are that and how to get them, nor is there indication of this thing going on to the same proportion nowadays as it was, considering the mathematical production is much higher. In mathematics human mathematicians have to decide which problems matter, it does not come from somewhere.

Solving "real" problems in theoretical mathematics (as in problems directly related to applications) is a very small proportion compared to the vast majority of math work that does not. So if we are discussing about the future of mathematics as a field, we have to understand what the field of theoretical mathematics is actually about.