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itvisionyesterday at 6:51 AM12 repliesview on HN

What a way to oversell the discovery.

The reality is:

    * Different brain regions have different functions: ancient knowledge.
    * Different regions contain distinct cell types and molecular programs: also well established.
    * Anterior and posterior brain structures may trace back to fundamentally separate progenitor lineages that were independently specified very early in evolution and development: that's the interesting new result.
The headline should have been: "Human forebrain and hindbrain arise from distinct embryonic progenitor lineages" - not that we have "two organs" in the brain.

Replies

xg15yesterday at 9:06 AM

> "Human forebrain and hindbrain arise from distinct embryonic progenitor lineages"

I'd have never clicked that headline nor understood why this finding is important.

If you think the original headline is not "truthful" enough, at least do something like "Researchers found the reason why hindbrain cells cannot be grown in a lab and found a way to overcome it"

> not that we have "two organs" in the brain.

Depends what the definition of "organ" actually is. What speaks for different organs here is that the cells both have a different pathway from stem cells and have different evolutionary histories. That is different from other brain regions that may have separate functions but still evolved together.

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sandeepkdyesterday at 6:58 AM

Though I agree with the detailed differentiation, still for the headline purpose a generic one that resonates with people easily isn't a bad choice

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jimnotgymyesterday at 9:09 AM

I don't have a problem with the 'two organs making one' framing. The fact that they are 'symbiotic' now doesn't change that. In fact it helps me understand two key facts. One can't grow out of the other, and they work differently. Great

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lucideeryesterday at 7:11 AM

Given the parallel example cited in the article of jellyfish having two spatially separate organs, & the subsequent speculation that our own ancestors could also have had spacially separate anterior & posterior masses, the title doesn't really seem unreasonable in its hyperbole.

While it might not be perfectly accurate it's hardly misleading.

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AltruisticGapHNyesterday at 9:13 AM

Main issue I have with the title is it immediately reminded me about McGilchrist's "The Divided Brain" and I thought they meant the two halves - but that is not the case.

So the question still remains...

https://www.ted.com/talks/iain_mcgilchrist_the_divided_brain

jijijijijyesterday at 10:36 AM

This is meaningless semantic drama over a meaningful discovery. From a biological and medical perspective, the collective term "organ" is pretty useless, if there is a distinct progenitor lineage. For the sake of a simplified explanation for the public, describing this discovery as finding "two organs" is absolutely fair.

A similar example: The melanocytes in the skin originate from the neural crest, not the epidermis. As a significant consequence, melanocytes share cell attributes with neurons. One of these attributes is the ability to infiltrate other tissues. Because of that, malignant transformation of melanocytes has vastly different consequences, compared to epithelial cells. If you asked your doctor why squamous cell cancer and melanoma have such different prognoses, describing your skin as effectively "two organs" would be illustrative and easy to understand, without getting into developmental biology.

Mistletoeyesterday at 7:55 AM

It’s the PR arm of a university, they always do this.

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nkmnzyesterday at 8:06 AM

I'm pretty sure the third thesis has been taught in my university physiology classes 20 years ago, too.

popalchemistyesterday at 7:58 AM

If the two parts arise independently, then the headline may be a bit clunky but it is technically correct.

akoboldfryingyesterday at 8:41 AM

Oh, I think we could crank that headline even harder while still keeping one toe on the truth. For example:

"Elon Musk's Brain is Two Separate Organs"

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t-writescodeyesterday at 6:57 AM

I mean, I learned a bunch of neat new stuff, so I’m excited!

lovichyesterday at 7:37 AM

Additionally the only images in the linked article are also face pics of the researchers instead of anything on the information about said research.

I want to trust science and dislike anti vaxxers but it’s difficult to argue against them when researchers act like the caricature they are mocked as.

Self aggrandizing articles with misleading headlines is giving me 2 triggers for not trusting the content.