What would be your idea of a biology problem that isn't an "engineering" one?

It seems that understanding biology could be characterized as trying to figure out "how did nature engineer this".

For that matter isn't all of science this way?

In a sense all experimental science has an element of engineering. For instance the first problem, "the origins of life" is framed to require an experiment to show that any proposed mechanism actually works.

Right? Where's the substrates of consciousness, or the actual solutions for protein/rna folding, or the requirements for evolution?

What else?