Yes and no? Certainly America has a bigger opioid market and Europe has a bigger ketamine market, for different reasons; America had a prescription opioid epidemic create its market, and Europe's much larger EDM party scene gravitated towards ketamine. Europeans also get much more treatment for opioid addiction (half of them!). But you never know what's going to change; America certainly didn't expect to be flooded with cheap prescription pills, and we can't predict if the drug lords of Europe will decide to start cutting their heroin with fentanyl.