Bubonic plague is known to be active in Colorado, I think there are a handful of cases each year
If you live in the Rocky Mountains try to avoid close contact with prairie dogs or animal carcasses and you'll be fine. If you catch it, get to a hospital quickly and take the antibiotics and you'll probably be fine. If you delay treatment you should use that time to get your affairs in order.
Endemic in Antananarivo (very many deaths per year), not sure about the rest of Madagascar.