My favorite combo is NextJS with static export and fastapi backend. Last three years I’ve done countless projects like this, now I just go forward with muscle memory.

For python just get SQLModel (that is basically SQLAlchemy + pydantic), alembic, develop in hexagonal architecture (or just follow the advanced architecture pattern with Python book) and that’s it.

For frontend, just go with tailwind, shadcn, tanstack...

Maybe in 10 years people will look at these technologies as I look at Oracle/JEE today, but they are making me so happy.