Sit down, think about the queries you are using, and think about how the tables are updated. Now take that and rethink your indexes. Use the right index type for the right situation, don’t just slap a basic index on a serial id field and call it a day. And while you’re at it, think about the ID fields you use, sometimes better options exist. UUIDv7 is now built in, use it.

Lots of things in PGSQL benefit from thinking about how your use case is manipulating the underlying B-tree, if you work in performance sensitive stuff the devil is really in the details. And having to rebuild indexes that have decayed over time is painful.