alt Hacker NewsMy wife was diagnosed in February with stage 4 invasive lobular breast cancer, peritoneal carcinomatosis with complete bowel obstruction. Surgeons gave her a couple weeks to live.
We went through enhertu which worked for about 3.5 months and relieved the blockage and she was able to eat again and get off IV nutrition. It obstructed again and her markers rose sharply in the summer, we did a course of taxol and are moving to trodelvy next week.
All of this has been entirely predictable, standard of care patterns.
But the standard of care for my wifes disease right now is a march toward death and I refuse to accept that.
I spend my every evening talking to every LLM, practically bargaining and begging for one of them to give me a thread of hope.
I appreciate this service and we will check it out. We are desperate to find something, I recognize ILC is tricky and complete obstruction is usually a death sentence, but we have to try right? She is 49, we have 4 kids.
Anyone out there, any ideas...any longshot, we will do anything.
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Disclaimer: talking out of my arse
Get LLMs to hillclimb your wife's treatment. The target isn't exactly verifiable but you could iterate on ways to add verification signals. There's a huge difference between asking an LLM: "hey claude, my wife has cancer, I want your help with x,y,z", which mode collapses it into extreme over-caution; versus setting up the problem like an eval, which sends LLMs into a frenzy trying to solve it no matter what.
Second thing I can share is the man who created an mRNA vaccine for his dog Rosie's cancer, and it worked! https://news.unsw.edu.au/en/meet-the-man-who-designed-a-canc...
Check out the documentary Forks Over Knives. It shows that cutting animal protein from your diet can combat cancer by starving it. Good luck!
Update: thank you for the downvote, whoever you are.
Very sorry to hear this.
Have you checked out any international Clinical Trials? You can search a lot of these here: https://clinicaltrials.gov/ getting the filters right can be tricky though. I’d ask AI for some help looking for the right permutations of names for things.
I’d book a call with FCCT as well. They have a list of private vendors that can potentially help with genetic sequencing and a few other things. They also mentioned a service to me that helps you search for potential clinical trials.