> They're now aware that they may never again have the joy of being the first to pull up the edge of the tarp of ignorance...
Not "never again", it would be extremely difficult but science and math are also built on random, trial and error, and intuitions that could not arise from AI.
That's the issue - trial and error. A human can try a couple ideas in a day, but realistically, there are not that many sane ideas.
Computer can iterate without frustration on a completely random garbage. Once in a while it stumbles upon a gem. Even if it's one in 10000, that's still hundreds of good ideas in a day (provided enough GPUs).