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gdulli • today at 3:32 AM • 2 replies • view on HN

We're adults like you are and can manage both our emotions and the responsibility of understanding that headlines aren't the totality of information.


Replies

ShinyLeftPad • today at 3:36 AM

When it is taking about a breakthrough in treatment of a human disease, it's kind of important if it's not actually in humans

Also "headlines aren't the totality of information" doesn't mean there's no clickbait headlines...

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jcranmer • today at 5:42 AM

The "... in mice" qualifier is somewhat overdone, but for Alzheimer's in particular, it's actually extremely important: mice do not experience Alzheimer's. We test Alzheimer's drugs in mice by artificially inducing something that produces similar dementia symptoms, and then seeing how the drugs influence that progression. If that model is different from how Alzheimer's works--and there's pretty decent suggestions from the history of failed Alzheimer's drugs in humans that our models of Alzheimer's are in fact wrong--then anything that fixes that model has suspect utility.