Dense models are not well suited to this. Depends on your system, but most inference engines let you put the KV cache on the host. They should let you use "Q8" KV cache format as well which takes half the storage of bf16, the default format. You essentially are stuck at having to fit the entire dense model into VRAM because it must compute across the entire model every token. Without it being in VRAM it is slow. MoE models such as Qwen 35B with 3B active parameters are much friendlier to limited VRAM systems. This is why you see systems with 16GB of VRAM running something like DeepSeek Flash if they have a bit of spare system RAM. Usually not at any good token rate, but tolerable.

Dense models also don't like quantization as much and are less tolerant of it. There are some very interesting smaller models like https://huggingface.co/nvidia/NVIDIA-Nemotron-Labs-Dory1.0-4... Dory that I would check out. You need system RAM or to stream a larger MoE model from disk and it won't be fast. You need to specialize the models some to get quality results if you have very limited system resources.