h264 was used in a homebrew port of Dragons Lair for the Nintendo 64: https://www.youtube.com/watch?v=i89f_CMn7bw
You can technically have some then-contemporary FMV titles run on N64 with a 64MB cart. The hardware lends itself to it because it has the RSP, a secondary MIPS processor with re-programmable microcode. But the best video compression we had at the time was MPEG-2, which just wouldn't cut it.
To be fair, the N64 port of Resident Evil 2 is still unbelievably cool and impressive, even being stuck with MPEG-2.