40 years of Thatcherism.
Good manufacturing jobs were gutted and sent overseas with no thought or care what the impact on communities would be. In some places families are now on the third generation on benefits because there simply aren't any jobs and the ones that are available require skills that people don't have because they aren't taught them in school due to the obsession with the Victorian education model and the shortage of skilled teachers and training opportunities for young people.
At this point nothing except for a total economic rebuild will save the UK high street and there is zero political will to do that because the current broken system makes certain people money.