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pedalpete • yesterday at 10:28 PM • 1 reply • view on HN

I'm curious if you've tried any methods to increase your endogenous GLP-1 activity?

These include things like loading your body earlier in the day with heavy protein and fermented foods, eating proteins and vegetables before carbs (make less room for carbs), and of course there is still the lower stress, improve sleep and exercise.

I'm not suggesting these are replacements, but potentially like a micro-dose response.


Replies

Sohcahtoa82 • yesterday at 10:53 PM

I'm not the GP, but I can answer this.

I did try keto before. Heavy protein, low carbs. Everyone promised a high protein/fat/fiber diet with low starch/sugar was the secret to feeling full sooner and for longer.

Nope. Didn't change a damn thing. I was still hungry all the time.

My experience mirrors the GP. Ozempic really flipped the switch. See my other comment (https://news.ycombinator.com/item?id=50399564) for more.