Outside bodybuilders I do not think they are popular.
Body builders are certainly on the forefront of biohacking, but the market is only getting bigger. Peptides are becoming popular in the same way that lifestyle HRT and tanning beds and plastic surgery and nutritional supplements are popular.
The obvious response would be Semaglutide which is a glucagon like peptide (GLP-1) made more main stream recently as a weight loss drug. You may have heard of it as the name Ozempic.
They are in wide use outside of that community