Americans are prudish, but not such that he would lose his job over an affair. A few Americans would boycott his company - but not enough to matter. There will be general disapproval, but that is as far as it will go.

However he will lose is job over an affair with someone that he has any form of business relationship with. He can have an affair with a nurse in the local hospital of the waitress of a local cafe and we will ignore it. However the girls he had an affair with are off-limits, and should be for any culture for reasons that we think should be obvious.