No, because you can get indistinguishable hand painted oil clones of famous paintings from Vietnamese rep shops and they obviously sell for far less than the originals.

Barring AI generated art and prose assets is valid, if for example you don't want to have the AI generation marker on steam, or you object to the use of AI for various ethical reasons. Also there's apparently quite the market of motivated purchasers that want to signal their anti AI values by buying from projects that don't use AI.