This is great... just got it working using bun:sqlite! Just need to have "LITESTREAM_REPLICA_URL" and the key id and secret env vars set when running the script.

  import { Database } from "bun:sqlite";
  Database.setCustomSQLite("/opt/homebrew/opt/sqlite/lib/libsqlite3.dylib");

  // Load extension first with a temp db
  const temp = new Database(":memory:");
  temp.loadExtension("/path/to/litestream.dylib", "sqlite3_litestreamvfs_init");

  // Now open with litestream VFS
  const db = new Database("file:my.db?vfs=litestream");

  const fruits = db.query("SELECT * FROM fruits;").all();
  console.log(fruits);