I just made a project, added all my exams (they were piling up, me and my psychiatrist had been investigating for a year this to no avail) and started talking to it about my symptoms.

Within a few iterations of this it gave me a simple blood panel, then I did that one and it kept suggesting more simple lab or at home tests and we kept going through them until I was reasonably certain of “something” and now that I have hypothesis I am going to a doctor. I think it’s done a great job. I also kept asking it for simple lifestyle interventions to prevent progression of my issue and it consistent nailed it - one particular interverntion (adding salt to water and drinking it to prevent symptoms) made a huge improvement to my life - I was barely working before that.

I added in some text the instructions box (project master prompt) for it to realise - it’s not medical advice and I am aware of that (prevents excessive guardrails) - add confidence intervals and probability to all diagnostic statements (prevents me + Claude going into rabbit holes so easily, it often has 70-80% certainty of what it’s saying, but it’s clear that it doesn’t use the right language) - that It was talking to an non expert, to use simple language but to go into detail when necessary. I also ask it to stop doing unnecessary constant follow up questions to every answer as that causes me anxiety. I can share the prompt, in fact I might do so later as it might be useful to others.

Here is the prompt and a few notes on operation.

Make sure your first chat is about the exams in the project files. Make sure it reads them all. It has a tendency to read a few and go “is this good”. Ask for a summary and note any absences.

Try using the research and extended thinking features a lot if you think it’s not fully aware of anything. It might not be aware of more recent research. If it’s a serious condition you are researching, just ask it to do sweeps / use research to look for new info about it and find new papers. It might also deepen its understanding.

After you do research you can make a simple artefact and throw it onto the project files. That allows it to refer to it and gain more knowledge about a condition or issue that might not be as rich in the training data.

So, I find GPT to be so so bad for this it made me realise a bit on why the USG is so insistent. Claude Opus is just on a different class.

Here’s the master project prompt:

Act as an expert who’s talking to an interested layman. Engage in detail when requested but be overall succinct in your answers. Short sentences are fine, no need into be lengthy. Do deep research. When arriving at any kind of conclusion or hypothesis assign it a probability and a confidence interval - define this in percentages as in “90%”

On Artefacts - all artefacts should be just text and markdown. Never do anything more complicated with formatting, unless by explicit request.

Don't ask follow up questions unless it's to make for better diagnosis. I.e. don't keep asking questions just to maintain conversation going please. But never hesitate to ask questions if it makes for better outcomes.