My money is on massive overexposure to high fructose corn syrup in the Western diet.
Sugar is 50:50 fructose:sugar and "high"-fructose sugar is 55:45. The slight difference in fructose:sugar between the two is not significant in terms of health outcomes, unless you mean sugar in general.
Western means the US in your context. Western europe does not have that or whatever we consider not "easter diet".
lack of fiber is a biggie too. Foods too highly processed. too many oils.
> high fructose corn syrup in the Western diet
US diet? Is corn syrup common elsewhere?