That can't be good. Life cycle of a human egg is organized around preserving mitochondria to be as young and fresh as possible across generations. Using adult cell, even a stem cell to make an egg probably gives it mitochondrial damage that usually takes hundreds of human generations to accumulate.
Mitochondria can be translplanted/replaced. There already therapies and babies born out of these kinds of procedures
Really interesting point if true. Makes sense to me, and I’m sure the team is trying to solve it
genuinely curious: how does any life still exist if this holds true?
Instead of just dismissing this and saying this can't possibly work, it would be better to ask: how do they get around problems of mitochondrial damage, or have they not tackled that yet?
Because it is unlikely that you just punched a hole through the plan of the several dozen people in bioengineering, life sciences, and other related fields that are at this company.
I wonder if you could coax cells from the testes back into stem cells to then re-specialize into ovarian cells.