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scotty79today at 6:26 AM5 repliesview on HN

That can't be good. Life cycle of a human egg is organized around preserving mitochondria to be as young and fresh as possible across generations. Using adult cell, even a stem cell to make an egg probably gives it mitochondrial damage that usually takes hundreds of human generations to accumulate.


Replies

treydtoday at 6:37 AM

I wonder if you could coax cells from the testes back into stem cells to then re-specialize into ovarian cells.

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Protostometoday at 6:43 AM

Mitochondria can be translplanted/replaced. There already therapies and babies born out of these kinds of procedures

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Jackobrientoday at 6:40 AM

Really interesting point if true. Makes sense to me, and I’m sure the team is trying to solve it

rf15today at 6:37 AM

genuinely curious: how does any life still exist if this holds true?

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khazhouxtoday at 7:45 AM

Instead of just dismissing this and saying this can't possibly work, it would be better to ask: how do they get around problems of mitochondrial damage, or have they not tackled that yet?

Because it is unlikely that you just punched a hole through the plan of the several dozen people in bioengineering, life sciences, and other related fields that are at this company.

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