alt Hacker NewsGlobal review confirms mRNA vaccines are safe, effective and full of promise
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Serious question in good faith: what was the deal with the “calamari” (clots?) the anti-vax crowd kept talking about being found in the veins/arteries of folks who took the Covid vaccine?
I really feel that many of the issues with mRNA vaccines and health studies in general are generalizations like “safe and effective”. Everything has statistical risks and benefits, and we should just share those front and center with people. Eg test results for X mean you have a Y% chance of having X, given your history and symptoms and other results. Here are low cost low risk marginal things you can do to improve statistical significance.
Similar for vaccines, just give us the numbers clearly and upfront.
This bypasses regulators from having to make claims beyond “we reviewed the data and agree with these numbers and feel that this should not be banned.” I do think it would also help to separate something “not banned” and being “required to be covered by insurance” or “required for professions like the military”. I think trying to simplify things makes things worse, because this abstraction is not real.
I'm not sure this information will sway very many people. I have relatives who are all getting tested for t-cell counts related to mRNA because they are convinced they are the cause of any and all health problems they are facing. It seems like the medical professionals who are administering the tests are at least somewhat responsible for their misapplication.
Shorter lead times in the face of viral mutations will be helpful.
Tailored vaccines for things like cancer are a game changer.
I live in hope of a semi-universal flu+related vaccine.
I live in fear of the measles induced "immune amnesia" effect.
how exactly were the vaccines effective, if every single person i know who got them got covid?
There are credible doctors and scientists who have a different view: https://maloneinstitute.org/reference-project
Really glad they confirmed this, about 5 years after I was forced to take one at threat of job loss despite 1) already having had natural Covid and 2) working a fully remote job.
But better late than never I suppose.
If these mRNA vaccines had not been pushed or mandated, more people would probably think they are safe: there will be no need for any of these reviews.
But because they were pushed by the government, many people do not trust them. Sure, they were pushed and mandated for good reasons, but the problem is that a lot of people have already lost trust in the government.
That trust was not lost because of one big decision. It was lost through many small, unrelated government decisions that may not seem noticeable or measurable on their own, but over time, they build up.
I do not know how this trust can be rebuilt but definitely not by publishing more reviews.
The potential for the technology in cancer treatment is what I find most exciting.
> The researchers emphasize that, like all vaccines, mRNA vaccines can have side effects. They found that serious adverse events—such as myocarditis, which occurs more frequently in younger males—are rare and consistently outweighed by the vaccines’ protection
reminder to the myocarditis-maxxies, the actual virus causes that too and the 2020-2021 variants caused it worse
if we were all going to drop dead (I think 2 years ago now, I’m waaaaiting!) for whatever the vaccine did, it would apply to a broader population due to covid exposure
The link in the article does not show the study, just a list of references, a summary and the researchers who published it. How many of the researchers who published this study have conflicts of interest? Where is the full study for review?
We synthesise evidence on vaccine components, manufacturing quality controls, and regulatory standards that underpin safety, alongside data from randomised trials, post-authorisation surveillance, and active pharmacovigilance systems.
"synthesize???"
With almost 200 references and the use of "synthesize???" it sound like AI generated slop.
The article is behind a paywall in any case so why so many positive comments about it?
The science doesn't matter to this administration unfortunately: https://www.bbc.com/news/articles/c74dzdddvmjo
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In the end, do facts even matter in politically charged discussions?
This sounds a bit like providing evidence for global warming, gun control or evolution. The "skeptics" just want to remain ignorant. No amount of evidence will change them.
The silver lining about vaccine skeptics, though, is the Herman Cain award[1]. What this means is that conservatives die more than liberals from preventable diseases [2].
You mean the stuff the whole world got injected with in 2020? Good to know!
Seriously though, I am very pro-vax, but the fact that studies like these come out now is just confirmation that people had the right to doubt the safety of mRNA back then. Many people shamed others for being anti vax but everyone has the right to be careful.
Two most populous countries, China and India, seem to have mainly relied on inactivated vaccines.
Good thing we got [rest of world] to do the hard science work, and America can just benefit from it instead!
Manufacturing matters, and six years ago, I said that one side effect from the pandemic is that mRNA technology, which had been lab-scale stuff, suddenly had dump-trucks full of money appearing to help them scale their manufacturing.
They apparently settled on the the sequences for the original covid vacs in a weekend. Going from that design to billions of doses is one of the hardest things to do, but once done, will persist. And it is ready to be deployed for the next hundred applications that we find for this.
Flu vaccines is an obvious application, since the prior egg-based manufacturing required about six months lead time and millions of eggs, but nobody wanted to invest in anything better.