alt Hacker NewsJust for the sake of honest balance, with minimal commentary and no opinions:
Acetaminophen and dementia correlation:
https://pmc.ncbi.nlm.nih.gov/articles/PMC2877629/
https://www.sciencedirect.com/science/article/abs/pii/S01638...
Note that it's also hard on the liver. A lot fatalities due to taking after hangovers, etc: https://www.medicalnewstoday.com/articles/322813 So if you insist, maybe take some NAC.
But apparently, Ibuprofen helps counter the dementia risk:
https://www.aan.com/PressRoom/home/PressRelease/624
I am not not asserting any clever marketing here. I am merely citing public information. Noting all the above, I am confident it's perfectly safe for children and fetuses, and if posing any risk at all, applies strictly to full grown adults. No doubts about child safety have been expressed here.
Replies
The liver toxicity is well known, and overdose is not uncommon.
The first paper shows no evidence of any effect from Tylenol...? But yeah seems like lots of support for the ibuprofen protective effect, interestingly.
This article is about "how early a child is born or a child’s weight at birth". I don't know why we're talking about other possible negatives of Acetaminophen. Seems off-topic to me.
"A lot fatalities due to taking after hangovers" no, that's not how acetaminophen fatalities happen. In fact, the article you cited specifically mentions "there is no scientific evidence that people with AUD (alcohol use disorder) who take the recommended dose of acetaminophen increase their risk of liver damage."
Fatalities happen basically from: product stacking combination medicines people don't realize contain acetaminophen and/or multi-day accumulation exceeding max daily limit over multiple days.
Chronic drinkers have impaired acetaminophen processing so they can't handle otherwise safe doses, but fatalities still typically occur in multi-day accumulation scenarios. Their safe daily max is ~half that of a non drinker.
The effects of one round of acute drinking don't impair the liver in the same way. People are not dropping dead because they took a normal dose of acetaminophen for a hangover. Not that I'm recommending you start doing it, but it is a myth.