I instruct my agents to build UI exclusively with bootstrap 5, jQuery, and HTMX.
Every app is fast, responsive, progressive, small, and most importantly: it fits in my brain and I can maintain it. No build step or really any tooling at all.
I've been thinking the same about the future of frameworks. Many of the complexities in today's frameworks exist for "developer experience", given that's less and less relevant by the month, it will be interesting to see the tech stacks chosen going forward.
Also a solid combination for LLM assisted apps. Claude Code will just get it. It's good with Tailwind also though.
IMO it is literally not possible for a medium+ jQuery app to fit in a brain or be maintained easily (especially without TypeScript). That's why React et al were invented. It is smaller, faster, no build step for sure, but I would never reach for jQuery for any possibly ambitious app.
If you are using mostly agents and don't actually need to have it in your brain, then I'd probably go with strict TypeScript at the very least for verifiability purposes
Even better than that - just use bootstrap 3
Curious what jQuery brings for you these days? My favorite jQuery features got implemented in the vanilla DOM APIs (document.querySelector and fetch being the big one for me). Now I'm curious if I'm missing out.