alt Hacker NewsThe "Potential Risks" section of the wiki is a bit thin on the mechanisms of the danger.
https://en.wikipedia.org/wiki/Mirror-image_life#Potential_ri...
'In December 2024, 38 scientists, including several synthetic biology researchers and two Nobel laureates, warned that the creation of mirror-image life could cause "unprecedented and irreversible harm" to human health and ecosystems worldwide. The reversed structure of mirror-image bacteria could allow them to evade many mechanisms critical for immunity and predation that have evolved to recognize natural-chirality structures. As a result, mirror-image bacteria could potentially escape immune defenses and invade natural ecosystems, leading to "pervasive lethal infections in a substantial fraction of plant and animal species, including humans."'
You don't need a mirror image organism to cause great harm. An engineered prion could also be devastating.
I don't think preons are technically mirror molecules, but it's close enough from a risk perspective. If rogue AI were to do us in through bioengineering, it might be by creating a novel prion.